STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wbpLGlycosyltransferase WbpL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (339 aa)    
Predicted Functional Partners:
wbpK
Probable NAD-dependent epimerase/dehydratase WbpK; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.992
wzy
B-band O-antigen polymerase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.981
wbpI
UDP-N-acetylglucosamine 2-epimerase WbpI; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the epimerization of UDP-2,3-diacetamido-2,3- dideoxy-alpha-D-glucuronic acid (UDP-alpha-D-GlcNAc3NAcA) to UDP-2,3- diacetamido-2,3-dideoxy-alpha-D-mannuronic acid (UDP-alpha-D- ManNAc3NAcA). Exhibits high specificity towards the substrate as UDP- alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2-acetamido-2-deoxy-alpha-D- glucuronic acid) and UDP-alpha-D-GlcNAc3NAc (UDP-2,3-diacetamido-2,3- dideoxy-alpha-D-glucose) cannot act as substrates. Belongs to the UDP-N-acetylgluc [...]
  
 0.977
wzz
O-antigen chain length regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.965
wbpJ
Probable glycosyl transferase WbpJ; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.964
wzx
O-antigen translocase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.959
wbpA
UDP-N-acetyl-d-glucosamine 6-Dehydrogenase; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP- N-acetylglucosaminuronic acid (UDP-D-GlcNAcA).
  
  
 0.958
wbpG
LPS biosynthesis protein WbpG; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.957
wbpH
Probable glycosyltransferase WbpH; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.954
wbpE
UDP-2-acetamido-2-dideoxy-d-ribo-hex-3-uluronic acid transaminase, wbpE; Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the amination of UDP-2-acetamido-2-deoxy-3-oxo- D-glucuronic acid (UDP-3-oxo-D-GlcNAcA) to UDP-2-acetamido-3-amino-2,3- dideoxy-D-glucuronic acid (UDP-GlcNAc3NA), using L-glutamate as the preferred amine donor; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.953
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.