STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpuA3-guanidinopropionase; Catalyzes the hydrolysis of 3-guanidinopropanoate to beta- alanine and urea. Possesses low activity against 4-guanidinobutanoate. Has no activity against arginine and agmatine. (318 aa)    
Predicted Functional Partners:
gpuP
3-guanidinopropionate transport protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.966
gpuR
Transcriptional activator GpuR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the LysR transcriptional regulatory family.
 
  
 0.959
PA1418
Probable sodium:solute symport protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.919
mntH2
Probable transporter; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
  
  
 0.789
hutG-2
Probable arginase family protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
  
  
 0.766
mntH1
Probable transport protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
  
  
 0.725
halS
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.662
PA4066
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.625
PA2914
Probable permease of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
   
  
 0.591
PA4063
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.588
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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