STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rarDHypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (299 aa)    
Predicted Functional Partners:
PA2018
Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
   
 0.897
PA4375
Probable Resistance-Nodulation-Cell Division (RND) efflux transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.882
PA3474
Conserved hypothetical protein; Uptake of biotin; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
 
    0.863
pheC
Cyclohexadienyl dehydratase precursor; Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions: prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport.
       0.536
putP
Sodium/proline symporter PutP; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
   
 0.453
rhlI
Autoinducer synthesis protein RhlI; Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to RhlR and thus acts in elastase biosynthesis regulation.
 
     0.433
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.