STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaECOG0587 DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]. (993 aa)    
Predicted Functional Partners:
holA
COG1466 DNA polymerase III, delta subunit [DNA replication, recombination, and repair].
  
 0.999
dnaN
COG0592 DNA polymerase sliding clamp subunit (PCNA homolog) [DNA replication, recombination, and repair].
    
 0.999
dnaX
DNA polymerase III gamma and tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.998
holB
PRK07132 DNA polymerase III subunit delta', Validated.
 
 0.997
ssb
COG0629 Single-stranded DNA-binding protein [DNA replication, recombination, and repair].
   
 
 0.995
exo
COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair].
  
 
 0.970
polC-2
DNA polymerase III polC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
0.950
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
  
 0.845
pheT
COG0072 Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; COG0073 EMAP domain [General function prediction only]; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
     
 0.685
metG
COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].
     
 0.567
Your Current Organism:
Mycoplasma arginini
NCBI taxonomy Id: 2094
Other names: ATCC 23838, CIP 71.23, IFO 14476, M. arginini, MRL M1240/68, Mycoplasma leonis, NBRC 14476, NCTC 10129, strain G230
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