STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exoCOG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair]. (292 aa)    
Predicted Functional Partners:
res
Type III restriction modification system endonuclease subunit Res; COG1061 DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].
  
 0.999
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.999
asnS
asparaginyl-tRNA-synthetase; COG0017 Aspartyl/asparaginyl-tRNA synthetases [Translation, ribosomal structure and biogenesis].
  
 0.999
dnaN
COG0592 DNA polymerase sliding clamp subunit (PCNA homolog) [DNA replication, recombination, and repair].
  
 0.999
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
 0.989
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.984
dinP
COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair].
  
 0.983
nei
foramidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.983
dnaE
COG0587 DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].
  
 
 0.970
uvrD
COG0210 Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].
   
 
 0.937
Your Current Organism:
Mycoplasma arginini
NCBI taxonomy Id: 2094
Other names: ATCC 23838, CIP 71.23, IFO 14476, M. arginini, MRL M1240/68, Mycoplasma leonis, NBRC 14476, NCTC 10129, strain G230
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.