STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prsARibose-phosphate pyrophosphokinase; COG0462 Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; COG1926 Predicted phosphoribosyltransferases [General function prediction only]. (323 aa)    
Predicted Functional Partners:
rpiB
COG0698 Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism].
    
 0.955
tktA
COG0021 Transketolase [Carbohydrate transport and metabolism]; COG3959 Transketolase, N-terminal subunit [Carbohydrate transport and metabolism].
   
 
 0.953
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
 0.908
ptc1
COG0631 Serine/threonine protein phosphatase [Signal transduction mechanisms].
   
 0.902
gidB
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.823
exo
COG0258 5'-3' exonuclease (including N-terminal domain of PolI) [DNA replication, recombination, and repair].
  
  
 0.790
metG
COG0143 Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].
  
 
 0.769
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
 
 0.713
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
    0.709
rpe
COG0036 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].
  
  
 0.622
Your Current Organism:
Mycoplasma arginini
NCBI taxonomy Id: 2094
Other names: ATCC 23838, CIP 71.23, IFO 14476, M. arginini, MRL M1240/68, Mycoplasma leonis, NBRC 14476, NCTC 10129, strain G230
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