STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOD25253.1Helicase, putative; Identified by sequence similarity; putative. (293 aa)    
Predicted Functional Partners:
metG
methionyl-tRNA synthetase; Identified by sequence similarity; putative.
  
  
 0.665
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.652
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
  0.626
pncB
Nicotinic acid phosphoribosyltransferase; Identified by sequence similarity; putative; Belongs to the NAPRTase family.
     
 0.603
AOD25251.1
Methyltransferase small domain protein; Identified by sequence similarity; putative; Belongs to the methyltransferase superfamily.
       0.586
AOD25506.1
5'-3' exonuclease family protein; Identified by sequence similarity; putative.
  
 
 0.573
AOD25320.1
ATP-dependent helicase PcrA; Identified by sequence similarity; putative.
  
 
 0.559
AOD25254.1
Hypothetical protein.
       0.524
potA
Spermidine/putrescine ABC transporter ATP-binding protein; Identified by sequence similarity; putative; Belongs to the ABC transporter superfamily.
   
 
 0.505
recA
Recombinase protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.433
Your Current Organism:
Mycoplasma hyorhinis
NCBI taxonomy Id: 2100
Other names: ATCC 17981, ATCC 23234, Asterococcus hyorhinis, CIP 104968, DSM 25591, IFO 14858, M. hyorhinis, NBRC 14858, NCTC 10130, strain BTS 7, strain BTS-7, strain BTS7, strain PG42
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.