STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhDDihydrolipoamide dehydrogenase; Identified by sequence similarity; putative. (629 aa)    
Predicted Functional Partners:
pdhC
Dihydrolipoamide acetyltransferase; Identified by sequence similarity; putative.
 0.999
pdhB
Pyruvate dehydrogenase E1 component beta subunit; Identified by sequence similarity; putative.
 
 0.999
pdhA
Pyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
AOD25023.1
Dihydrolipoamide dehydrogenase; Identified by sequence similarity; putative.
 
0.997
prs
Ribose-phosphate pyrophosphokinase; Identified by sequence similarity; putative.
  
 0.995
AOD25304.1
Glycine cleavage system H protein; Identified by sequence similarity; putative.
  
 0.991
glyA
Serine hydroxymethyltransferase 3; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.969
AOD25107.1
Lipoate-protein ligase A; Identified by sequence similarity; putative.
  
 0.933
AOD25306.1
Lipoate-protein ligase A; Identified by sequence similarity; putative.
  
 0.930
AOD25442.1
Protein phosphatase 2C-like protein; Identified by sequence similarity; putative.
  
 0.915
Your Current Organism:
Mycoplasma hyorhinis
NCBI taxonomy Id: 2100
Other names: ATCC 17981, ATCC 23234, Asterococcus hyorhinis, CIP 104968, DSM 25591, IFO 14858, M. hyorhinis, NBRC 14858, NCTC 10130, strain BTS 7, strain BTS-7, strain BTS7, strain PG42
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