STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaIPutative primosomal protein; Identified by sequence similarity; putative. (289 aa)    
Predicted Functional Partners:
dnaC
Replicative helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.989
AOD25664.1
Chromosome replication initiation and membrane attachment protein; Identified by sequence similarity; putative.
  
  
 0.867
AOD25663.1
Putative dephospho-CoA kinase; Identified by sequence similarity; putative.
       0.668
AOD25506.1
5'-3' exonuclease family protein; Identified by sequence similarity; putative.
     
 0.643
AOD25618.1
DUTPase; Identified by sequence similarity; putative.
 
     0.604
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
   
 0.530
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.487
AOD25662.1
COF family HAD hydrolase protein; Identified by sequence similarity; putative.
       0.425
dnaE
DNA polymerase III alpha subunit; Identified by sequence similarity; putative.
     
 0.412
AOD25654.1
ABC transport system permease protein p69; Identified by sequence similarity; putative.
 
     0.400
Your Current Organism:
Mycoplasma hyorhinis
NCBI taxonomy Id: 2100
Other names: ATCC 17981, ATCC 23234, Asterococcus hyorhinis, CIP 104968, DSM 25591, IFO 14858, M. hyorhinis, NBRC 14858, NCTC 10130, strain BTS 7, strain BTS-7, strain BTS7, strain PG42
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.