STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_1109cPutative integral membrane protein; Best Blastp Hit: gb|AAF41787.1| (AE002492) hypothetical protein [Neisseria meningitidis MC58] >gi|7380281|emb|CAB84867.1| (AL162756) putative integral membrane protein [Neisseria meningitidis]. (417 aa)    
Predicted Functional Partners:
sloA
Putative ABC transporter, ATP-binding protein; Best Blastp Hit: gb|AAF81672.1|AF232688_1 (AF232688) SloA [Streptococcus mutans].
   
  
 0.526
sloB
Putative Mn/Zn ABC transporter; Best Blastp Hit: gb|AAF81673.1|AF232688_2 (AF232688) SloB [Streptococcus mutans].
   
  
 0.517
SMU_1111c
Conserved hypothetical protein; Best Blastp Hit: sp|P31847|YPUA_BACSU HYPOTHETICAL 31.3 KD PROTEIN IN LYSA-PPIB INTERGENIC REGION (ORFX19) >gi|1075852|pir||JU0473 ypuA protein - Bacillus subtilis >gi|410118|gb|AAA67474.1| (L09228) ORFX19 [Bacillus subtilis] >gi|2634772|emb|CAB14269.1| (Z99116) ypuA [Bacillus subtilis].
       0.477
SMU_1108c
Conserved hypothetical protein; Best Blastp Hit: dbj|BAA35548.1| (D90722) Hypothetical 30.2 kd protein in idh-deoR intergenic region. [Escherichia coli] >gi|4062435|dbj|BAA35556.1| (D90723) Hypothetical 30.2 kd protein in idh-deoR intergenic region. [Escherichia coli].
       0.437
sloC
Putative ABC transporter, metal binding lipoprotein; Part of an ATP-driven transport system for a metal; probably for manganese. Also acts as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection. It may contribute to the formation and accumulation of dental plaque; Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily.
   
  
 0.401
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.