STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_1209cHypothetical protein; Best Blastp Hit: gi|6715600 golgi autoantigen, golgin subfamily a, 4; golgin 245; golgin-240; p230 [Homo sapiens] >gi|1213484|gb|AAC50434.1| (U41740) trans-Golgi p230 [Homo sapiens] >gi|1589554|prf||2211333A peripheral membrane protein p230 [Homo sapiens]. (446 aa)    
Predicted Functional Partners:
parE
Putative DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.
       0.741
SMU_2152c
Conserved hypothetical protein; Best Blastp Hit: gb|AAC61482.1| (AF082738) unknown [Streptococcus pyogenes].
      
 0.623
SMU_521
Conserved hypothetical protein; Best Blastp Hit: dbj|BAB07152.1| (AP001518) unknown conserved protein in B. subtilis [Bacillus halodurans].
      
 0.599
SMU_843
Conserved hypothetical protein; Best Blastp Hit: gi|10956446 pXO2-56 [Bacillus anthracis] >gi|6470207|gb|AAF13661.1|AF188935_59 (AF188935) pXO2-56 [Bacillus anthracis].
      
 0.599
pyrK
Putative dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
      
 0.597
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
       0.520
SMU_1194
Best Blastp Hit: pir||G71842 probable ABC transporter, ATP-binding protein - Helicobacter pylori (strain J99) >gi|4155748|gb|AAD06727.1| (AE001542) putative ABC transporter, ATP-binding protein [Helicobacter pylori J99].
      
 0.450
trpB
Putative tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
      
 0.420
SMU_1208c
Hypothetical protein; Best Blastp Hit: pir||A59282 nonmuscle myosin II heavy chain A - African clawed frog >gi|3660672|gb|AAC83556.1| (AF055895) nonmuscle myosin II heavy chain A [Xenopus laevis].
       0.414
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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