STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_1463cConserved hypothetical protein; Best Blastp Hit: dbj|BAA11246.1| (D78182) ORF4 [Streptococcus mutans]. (262 aa)    
Predicted Functional Partners:
SMU_1464c
Conserved hypothetical protein; Best Blastp Hit: dbj|BAA11245.1| (D78182) ORF3 [Streptococcus mutans].
  
 0.966
SMU_1465c
Conserved hypothetical protein; Best Blastp Hit: dbj|BAA11244.1| (D78182) ORF2 [Streptococcus mutans].
       0.800
metA
Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
       0.800
SMU_1462c
Putative oxidoreductase; Best Blastp Hit: sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-MRGA INTERGENIC REGION >gi|7475684|pir||A70019 opine catabolism homolog yurR - Bacillus subtilis >gi|2635760|emb|CAB15253.1| (Z99120) similar to opine catabolism [Bacillus subtilis].
       0.730
apt
Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
    0.592
rmlA
Putative glucose-1-phosphate thymidyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
       0.586
rmlC
Best Blastp Hit: dbj|BAA11248.1| (D78182) dTDP-4-keto-L-rhamnose reductase [Streptococcus mutans].
       0.432
rmlB
Putative dTDP-glucose-4,6-dehydratase; Catalyzes the dehydration of dTDP-D-glucose to form dTDP-6- deoxy-D-xylo-4-hexulose via a three-step process involving oxidation, dehydration and reduction.
  
    0.421
pepT
Putative tripeptidase (peptidase T); Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
    0.413
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.