STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_1487Best Blastp Hit: pir||D72115 conserved hypothetical protein CP0630 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4376408|gb|AAD18296.1| (AE001600) Hypothetical Protein [Chlamydophila pneumoniae] >gi|7189544|gb|AAF38445.1| (AE002221) conserved hypothetical protein [Chlamydophila pneumoniae AR39] >gi|8978516|dbj|BAA98353.1| (AP002545) hypothetical protein [Chlamydophila pneumoniae]. (381 aa)    
Predicted Functional Partners:
SMU_874
Conserved hypothetical protein; Best Blastp Hit: dbj|BAB05348.1| (AP001512) unknown conserved protein [Bacillus halodurans].
  
 
 0.951
metK
Putative S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.596
SMU_1484c
Conserved hypothetical protein; Best Blastp Hit: emb|CAB72624.1| (AL139074) hypothetical protein Cj0140 [Campylobacter jejuni].
 
     0.561
SMU_1485c
Putative endonuclease; Best Blastp Hit: emb|CAB72623.1| (AL139074) putative endonuclease [Campylobacter jejuni].
 
     0.542
SMU_1486c
Best Blastp Hit: pir||E72330 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981334|gb|AAD35886.1|AE001748_2 (AE001748) conserved hypothetical protein [Thermotoga maritima]; Belongs to the PHP hydrolase family. HisK subfamily.
       0.537
cpsY
Putative transcriptional regulator; Best Blastp Hit: pir||T44638 capsular polysaccharide biosynthesis protein cpsY [imported] - Streptococcus agalactiae >gi|4456788|emb|CAB36980.1| (Y17218) CpsY protein [Streptococcus agalactiae] >gi|4467988|emb|CAB36982.2| (Y17241) CpsY protein [Streptococcus agalactiae] >gi|5823210|gb|AAD53064.1|AF163833_1 (AF163833) CpsY [Streptococcus agalactiae]; Belongs to the LysR transcriptional regulatory family.
 
  
 0.520
metB
Putative cystathionine gamma-synthase; Best Blastp Hit: pir||G64047 cystathionine gamma-lyase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573037|gb|AAC21764.1| (U32694) cystathionine gamma-synthase (metB) [Haemophilus influenzae Rd] 4.4.1.1 cystathionine gamma-lyase or cystathionine beta-lyases 4.4.8.1.
  
  
 0.499
SMU_930c
Putative transcriptional regulator; Best Blastp Hit: pir||T44638 capsular polysaccharide biosynthesis protein cpsY [imported] - Streptococcus agalactiae >gi|4456788|emb|CAB36980.1| (Y17218) CpsY protein [Streptococcus agalactiae] >gi|4467988|emb|CAB36982.2| (Y17241) CpsY protein [Streptococcus agalactiae] >gi|5823210|gb|AAD53064.1|AF163833_1 (AF163833) CpsY [Streptococcus agalactiae]; Belongs to the LysR transcriptional regulatory family.
 
  
 0.488
luxS
Putative autoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
   
 0.478
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
     
 0.423
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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