STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgAPutative starch (bacterial glycogen) synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (476 aa)    
Predicted Functional Partners:
glgD
Putative glycogen biosynthesis protein GlgD; Best Blastp Hit: dbj|BAB04805.1| (AP001510) required for glycogen biosynthesis [Bacillus halodurans].
 
 0.999
glgC
Putative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 0.999
glgB
Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.999
phsG
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.994
malQ
Best Blastp Hit: sp|P29851|MALQ_STRPN 4-ALPHA-GLUCANOTRANSFERASE (AMYLOMALTASE) (DISPROPORTIONATING ENZYME) (D-ENZYME) >gi|153704|gb|AAA26923.1| (J01796) amylomaltase [Streptococcus pneumoniae].
 
 
 0.958
glgP
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
  
 0.945
pulA
Putative pullulanase; Best Blastp Hit: prf||1808262A thermostable pullulanase [Bacillus stearothermophilus]; Belongs to the glycosyl hydrolase 13 family.
 
  
 0.942
adhE
Best Blastp Hit: emb|CAA04467.1| (AJ001008) Alcohol-acetaldehyde dehydrogenase [Lactococcus lactis]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.927
SMU_2127
Best Blastp Hit: gb|AAD19405.1| (AF102543) succinic semialdehyde dehydrogenase [Zymomonas mobilis]; Belongs to the aldehyde dehydrogenase family.
  
  
 0.813
msmF
Multiple sugar-binding ABC transporter, permease protein MsmF; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
  
    0.744
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.