node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_2165 | ssb2 | SMU_2165 | SMU_1967 | Putative SpoJ; Belongs to the ParB family. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.793 |
SMU_2165 | topA | SMU_2165 | SMU_1002 | Putative SpoJ; Belongs to the ParB family. | Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.439 |
comYA | comYB | SMU_1987 | SMU_1985 | Best Blastp Hit: gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]. | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | 0.999 |
comYA | smf | SMU_1987 | SMU_1001 | Best Blastp Hit: gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]. | Putative DNA processing Smf protein; Best Blastp Hit: sp|P39813|SMF_BACSU SMF PROTEIN >gi|7474815|pir||H69708 DNA processing Smf protein homolog smf - Bacillus subtilis >gi|2462969|emb|CAA04421.1| (AJ000975) Smf protein [Bacillus subtilis] >gi|2633983|emb|CAB13484.1| (Z99112) DNA processing Smf protein homolog [Bacillus subtilis]. | 0.813 |
comYA | ssb | SMU_1987 | SMU_1859 | Best Blastp Hit: gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.502 |
comYA | ssb2 | SMU_1987 | SMU_1967 | Best Blastp Hit: gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.742 |
comYB | comYA | SMU_1985 | SMU_1987 | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | Best Blastp Hit: gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]. | 0.999 |
comYB | smf | SMU_1985 | SMU_1001 | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | Putative DNA processing Smf protein; Best Blastp Hit: sp|P39813|SMF_BACSU SMF PROTEIN >gi|7474815|pir||H69708 DNA processing Smf protein homolog smf - Bacillus subtilis >gi|2462969|emb|CAA04421.1| (AJ000975) Smf protein [Bacillus subtilis] >gi|2633983|emb|CAB13484.1| (Z99112) DNA processing Smf protein homolog [Bacillus subtilis]. | 0.700 |
comYB | ssb2 | SMU_1985 | SMU_1967 | Best Blastp Hit: gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.640 |
dnaE | dnaX | SMU_1192 | SMU_1581 | DNA polymerase III, alpha chain; Best Blastp Hit: gb|AAF98350.1| (AF280766) DNA polymerase III alpha subunit [Streptococcus pyogenes]. | DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.999 |
dnaE | ssb | SMU_1192 | SMU_1859 | DNA polymerase III, alpha chain; Best Blastp Hit: gb|AAF98350.1| (AF280766) DNA polymerase III alpha subunit [Streptococcus pyogenes]. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.746 |
dnaE | ssb2 | SMU_1192 | SMU_1967 | DNA polymerase III, alpha chain; Best Blastp Hit: gb|AAF98350.1| (AF280766) DNA polymerase III alpha subunit [Streptococcus pyogenes]. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.706 |
dnaE | topA | SMU_1192 | SMU_1002 | DNA polymerase III, alpha chain; Best Blastp Hit: gb|AAF98350.1| (AF280766) DNA polymerase III alpha subunit [Streptococcus pyogenes]. | Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.613 |
dnaX | dnaE | SMU_1581 | SMU_1192 | DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, alpha chain; Best Blastp Hit: gb|AAF98350.1| (AF280766) DNA polymerase III alpha subunit [Streptococcus pyogenes]. | 0.999 |
dnaX | ssb | SMU_1581 | SMU_1859 | DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.717 |
dnaX | ssb2 | SMU_1581 | SMU_1967 | DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.710 |
dnaX | topA | SMU_1581 | SMU_1002 | DNA polymerase III, gamma/tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Putative DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing [...] | 0.532 |
priA | ssb | SMU_480 | SMU_1859 | Primosomal replication factor Y (primosomal protein N'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.658 |
priA | ssb2 | SMU_480 | SMU_1967 | Primosomal replication factor Y (primosomal protein N'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.711 |
rs6 | ssb | SMU_1860 | SMU_1859 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | Putative single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.933 |