STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_373Hypothetical protein; Best Blastp Hit: pir||C75210 sterol biosynthesis methyltransferase related PAB2213 - Pyrococcus abyssi (strain Orsay) >gi|5457639|emb|CAB49130.1| (AJ248283) sterol biosynthesis methyltransferase related [Pyrococcus abyssi]. (247 aa)    
Predicted Functional Partners:
SMU_374
Putative oxidoreductase; Best Blastp Hit: sp|P80869|DHG2_BACSU GLUCOSE 1-DEHYDROGENASE II (GLCDH-II) (GDH-II) (GENERAL STRESS PROTEIN 74) (GSP74)## >gi|7430991|pir||G69755 glucose 1-dehydrogenase homolog ycdF - Bacillus subtilis >gi|2415734|dbj|BAA22244.1| (AB000617) YcdF [Bacillus subtilis] >gi|2632569|emb|CAB12077.1| (Z99105) similar to glucose 1-dehydrogenase [Bacillus subtilis].
   
 
 0.794
SMU_372
Best Blastp Hit: gi|6321352 coil protein involved in the spindle-assembly checkpoint; Mad1p [Saccharomyces cerevisiae] >gi|729975|sp|P40957|MAD1_YEAST SPINDLE ASSEMBLY CHECKPOINT COMPONENT MAD1 (MITOTIC MAD1 PROTEIN) >gi|1362416|pir||A57276 MAD1 protein - yeast (Saccharomyces cerevisiae) >gi|551092|gb|AAA91620.1| (U14632) Mad1p [Saccharomyces cerevisiae] >gi|1322611|emb|CAA96791.1| (Z72608) ORF YGL086w [Saccharomyces cerevisiae].
       0.785
SMU_375
Hypothetical protein; Best Blastp Hit: pir||F70091 hypothetical protein yydH - Bacillus subtilis >gi|1064788|dbj|BAA11274.1| (D78193) yydH [Bacillus subtilis] >gi|2636563|emb|CAB16053.1| (Z99124) yydH [Bacillus subtilis].
       0.769
SMU_376
Putative aminotransferase; Best Blastp Hit: sp|O66442|ARGD_AQUAE ACETYLORNITHINE AMINOTRANSFERASE (ACOAT) >gi|7434134|pir||G70301 N-acetylornithine aminotransferase - Aquifex aeolicus >gi|2982764|gb|AAC06390.1| (AE000669) N-acetylornithine aminotransferase [Aquifex aeolicus]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.716
SMU_370
Best Blastp Hit: dbj|BAB07612.1| (AP001520) ABC transporter (ATP-binding protein) [Bacillus halodurans].
       0.628
SMU_371
Conserved hypothetical protein; inner membrane protein.
       0.628
SMU_378
Hypothetical protein.
       0.419
SMU_379
Hypothetical protein.
       0.419
birA
Putative biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.418
bacA1
Best Blastp Hit: sp|O68006|BACA_BACLI BACITRACIN SYNTHETASE 1 (BA1) [INCLUDES: ATP-DEPENDENT ISOLEUCINE ADENYLASE (ILEA) (ISOLEUCINE ACTIVASE); ATP-DEPENDENT CYSTEINE ADENYLASE (CYSA) (CYSTEINE ACTIVASE); ATP-DEPENDENT LEUCINE ADENYLASE (LEUA) (LEUCINE ACTIVASE); ATP-DEPENDENT GLUTAMATE AD> >gi|7474354|pir||T31677 bacitracin synthetase 1 - Bacillus licheniformis >gi|2982194|gb|AAC06346.1| (AF007865) bacitracin synthetase 1; BacA [Bacillus licheniformis].
     
 0.400
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.