STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbp1aBest Blastp Hit: pir||S28031 penicillin-binding protein 1a - Streptococcus pneumoniae (strain 456) (fragment) >gi|47406|emb|CAA48068.1| (X67868) penicillin-binding protein 1a [Streptococcus pneumoniae] >gi|5410457|gb|AAD43066.1|AF139883_1 (AF139883) penicillin-binding protein 1a [Streptococcus pneumoniae]. (707 aa)    
Predicted Functional Partners:
pbp2x
Putative penicillin-binding protein 2X; Best Blastp Hit: gb|AAF17264.1|AF210754_1 (AF210754) penicillin-binding protein 2X [Streptococcus pneumoniae].
 
 
 0.995
pbp2b
Penicillin-binding protein 2b; Best Blastp Hit: gb|AAC44614.1| (U58210) penicillin-binding protein 2b [Streptococcus thermophilus].
 
 0.993
pbp1b
Best Blastp Hit: emb|CAA05302.1| (AJ002291) penicillin-binding protein 1b [Streptococcus pneumoniae] >gi|6165962|gb|AAF04736.1|AF101781_1 (AF101781) penicillin-binding protein 1b [Streptococcus pneumoniae].
  
 
0.949
pbp2a
Best Blastp Hit: gb|AAF04735.1|AF101780_1 (AF101780) penicillin-binding protein 2a [Streptococcus pneumoniae].
  
 
0.946
dacA
Putative D-alanyl-D-alanine carboxypeptidase; Best Blastp Hit: emb|CAA67776.1| (X99400) D,D-carboxypeptidase [Streptococcus pneumoniae]; Belongs to the peptidase S11 family.
  
 
 0.924
gpsB
Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
 
 
 0.916
SMU_75
Best Blastp Hit: gb|AAD00280.1| (U78599) putative D,D-carboxypeptidase [Streptococcus mutans].
     
 0.902
ftsW
Best Blastp Hit: sp|Q47866|FTSW_ENTHR PROBABLE CELL DIVISION PROTEIN FTSW >gi|1469784|gb|AAB39929.1| (U58049) putative cell division protein ftsW [Enterococcus hirae]; Belongs to the SEDS family.
  
 
 0.818
mreC
Putative cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
 
 0.796
SMU_1279c
Putative cell division protein (cell shape determining protein); Best Blastp Hit: dbj|BAB06994.1| (AP001518) stage V sporulation protein E [Bacillus halodurans]; Belongs to the SEDS family.
  
 
 
 0.744
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.