STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agaLAlpha-galactosidase; Best Blastp Hit: sp|P27756|AGAL_STRMU ALPHA-GALACTOSIDASE (MELIBIASE) >gi|322116|pir||A44819 alpha-galactosidase (EC 3.2.1.22) - Streptococcus mutans >gi|153736|gb|AAA26933.1| (M77351) a-galactosidase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 36 family. (720 aa)    
Predicted Functional Partners:
gtfA
Sucrose phosphorylase, GtfA; Intracellular catabolism of sucrose. Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.
 
  
 0.973
msmE
Multiple sugar-binding ABC transporter, sugar-binding protein precursor MsmE; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose.
 
  
 0.968
msmG
Multiple sugar-binding ABC transporter, permease protein MsmG; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
 
  
 0.954
msmF
Multiple sugar-binding ABC transporter, permease protein MsmF; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
 
  
 0.942
scrB
Best Blastp Hit: sp|P13522|SCRB_STRMU SUCROSE-6-PHOSPHATE## HYDROLASE (SUCRASE) (INVERTASE) >gi|97999|pir||A43501 sucrose-6-phosphate hydrolase - Streptococcus mutans >gi|47259|emb|CAA35872.1| (X51507) sucrose-6-phosphate hydrolase [Streptococcus mutans] >gi|153804|gb|AAA26972.1| (M36849) sucrose-6-phosphate hydrolase [Streptococcus mutans].
 
 
 0.930
msmR
Putative MSM operon regulatory protein; Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes.
 
  
 0.893
dexB
Dextran glucosidase DexB; The physiological substrates may be short isomaltosaccharides.
 
  
 0.825
galK
Galactokinase, GalK; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
  
 0.726
SMU_104
Putative alpha-glucosidase; Best Blastp Hit: emb|CAB99206.1| (AJ251975) alpha-xylosidase [Sulfolobus solfataricus]; Belongs to the glycosyl hydrolase 31 family.
 
   
 0.718
galT
galactose-1-P-uridyl transferase, GalT; Best Blastp Hit: sp|P96994|GAL7_STRMU GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (GAL-1-P URIDYLYLTRANSFERASE) >gi|7448853|pir||JC5312 UTP--hexose-1-phosphate uridylyltransferase (EC 2.7.7.10) - Streptococcus mutans >gi|1877423|gb|AAB49737.1| (U21942) galactose-1-P-uridyl transferase [Streptococcus mutans].
 
  
 0.696
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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