STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_928Putative histidine kinase; Best Blastp Hit: gb|AAF79919.1| (AF039082) putative histidine protein kinase [Lactococcus lactis]. (412 aa)    
Predicted Functional Partners:
SMU_927
Putative response regulator; Best Blastp Hit: pir||D70624 probable two-component regulatory protein - Mycobacterium tuberculosis (strain H37RV) >gi|1869995|emb|CAB06846.1| (Z92539) hypothetical protein Rv1033c [Mycobacterium tuberculosis] >gi|2979514|gb|AAC06144.1| (U88959) response regulator homolog TrcR [Mycobacterium tuberculosis].
 
 
 0.995
ciaR
Best Blastp Hit: emb|CAB54564.1| (AJ005926) response regulator [Streptococcus pneumoniae].
 
 
 0.962
SMU_926
Conserved hypothetical protein; Best Blastp Hit: dbj|BAB05604.1| (AP001513) unknown conserved protein [Bacillus halodurans].
 
   
 0.944
adhD
Best Blastp Hit: pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum].
    
 0.928
gcrR
Response regulator GcrR for glucan-binding protein C; Best Blastp Hit: dbj|BAA85986.1| (AB024522) gcrR [Streptococcus mutans].
 
 
 0.741
scnK
Putative histidine kinase, ScnK-like protein; Best Blastp Hit: pir||T09002 histidine kinase homolog scnK - Streptococcus pyogenes >gi|2502066|gb|AAB92598.1| (AF026542) ScnK [Streptococcus pyogenes].
  
 
 0.732
SMU_1965c
Putative histidine kinase; Best Blastp Hit: pir||T34676 probable sensor kinase - Streptomyces coelicolor >gi|4007712|emb|CAA22397.1| (AL034446) putative sensor kinase [Streptomyces coelicolor A3(2)].
   
 
 0.684
SMU_1146c
Putative response regulator; Similar to RumR and ScnR; Best Blastp Hit: pir||T09003 response regulator homolog scnR - Streptococcus pyogenes >gi|2502067|gb|AAB92599.1| (AF026542) ScnR [Streptococcus pyogenes].
 
 
 0.676
SMU_1038c
Putative response regulator; Best Blastp Hit: dbj|BAB04539.1| (AP001509) two-component response regulator [Bacillus halodurans].
 
 
 0.671
scnR
Best Blastp Hit: pir||T09003 response regulator homolog scnR - Streptococcus pyogenes >gi|2502067|gb|AAB92599.1| (AF026542) ScnR [Streptococcus pyogenes].
 
 
 0.659
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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