STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_937Best Blastp Hit: gb|AAG02456.1|AF290099_2 (AF290099) mevalonate diphosphate decarboxylase [Streptococcus pneumoniae]. (310 aa)    
Predicted Functional Partners:
SMU_938
Putative phosphomevalonate kinase; Best Blastp Hit: gb|AAG02452.1|AF290097_3 (AF290097) phosphomevalonate kinase [Streptococcus pyogenes].
 
 
 0.998
fni
Putative dehydrogenase (FMN-dependent family protein); Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.995
SMU_582
Putative farnesyl diphosphate synthase; Best Blastp Hit: sp|O66126|ISPA_MICLU GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP SYNTHASE) >gi|2982677|dbj|BAA25265.1| (AB003187) farnesyl diphosphate synthase [Micrococcus luteus]; Belongs to the FPP/GGPP synthase family.
  
 0.943
SMU_181
Putative mevalonate kinase; Best Blastp Hit: gb|AAG02440.1|AF290093_1 (AF290093) mevalonate kinase [Enterococcus faecalis].
 
  
 0.931
SMU_943c
Putative hydroxymethylglutaryl-CoA synthase; Best Blastp Hit: gb|AAG02453.1|AF290098_1 (AF290098)## HMG-CoA synthase [Streptococcus pneumoniae].
 
 
 0.912
mvaA
Putative hydroxymethylglutaryl-CoA reductase; Best Blastp Hit: gb|AAG02449.1|AF290096_2 (AF290096) HMG-CoA reductase [Streptococcus pyogenes].
 
  
 0.851
lysS
lysyl-tRNA synthetase; Best Blastp Hit: sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|2127132|pir||S66111 lysine--tRNA ligase (EC 6.1.1.6) lysS - Bacillus subtilis >gi|467470|dbj|BAA05316.1| (D26185) lysyl-tRNA thynthetase [Bacillus subtilis] >gi|2632349|emb|CAB11858.1| (Z99104) lysyl-tRNA synthetase [Bacillus subtilis]; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.527
SMU_935
Best Blastp Hit: sp|O34931|YTMM_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER PERMEASE PROTEIN YTMM >gi|7442389|pir||G69996 amino acid ABC transporter (permease) homolog ytmM - Bacillus subtilis >gi|2293250|gb|AAC00328.1| (AF008220) transporter [Bacillus subtilis] >gi|2635400|emb|CAB14895.1| (Z99118) similar to amino acid ABC transporter (permease) [Bacillus subtilis] >gi|2635419|emb|CAB14913.1| (Z99119) similar to amino acid ABC transporter (permease) [Bacillus subtilis].
       0.463
SMU_934
Best Blastp Hit: sp|O34315|YTML_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER PERMEASE PROTEIN YTML >gi|7442387|pir||F69996 amino acid ABC transporter (permease) homolog ytmL - Bacillus subtilis >gi|2293249|gb|AAC00327.1| (AF008220) amino acid transporter [Bacillus subtilis] >gi|2635401|emb|CAB14896.1| (Z99118) similar to amino acid ABC transporter (permease) [Bacillus subtilis] >gi|2635420|emb|CAB14914.1| (Z99119) similar to amino acid ABC transporter (permease) [Bacillus subtilis].
       0.445
SMU_936
Best Blastp Hit: sp|O34900|YTMN_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN YTMN >gi|7442519|pir||F69641 histidine transport protein hisP - Bacillus subtilis >gi|2293251|gb|AAC00329.1| (AF008220) putative amino acid transporter [Bacillus subtilis] >gi|2635399|emb|CAB14894.1| (Z99118) histidine transport protein (ATP-binding protein) [Bacillus subtilis] >gi|2635418|emb|CAB14912.1| (Z99119) histidine transport protein (ATP-binding protein) [Bacillus subtilis].
       0.440
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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