STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqnCDehypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (354 aa)    
Predicted Functional Partners:
mqnD
S-ribosylhomocysteine lyase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
  
 0.970
OHU84482.1
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.878
OHU82496.1
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.859
OHU85281.1
4-hydroxybenzoate polyprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family.
 
   
 0.794
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.740
OHU85610.1
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.728
OHU85911.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
  0.661
OHU84685.1
Menaquinone biosynthesis decarboxylase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UbiD family.
 
   
 0.660
OHU84812.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
   
 0.616
OHU84858.1
Flagellar biosynthesis protein FlgG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.610
Your Current Organism:
Helicobacter sp. CLO3
NCBI taxonomy Id: 211
Other names: Campylobacter-like organism 3, H. sp. CLO-3, Helicobacter CLO3, Helicobacter sp. (strain CLO3), Helicobacter sp. CLO-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.