STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM19964.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1186 aa)    
Predicted Functional Partners:
SDN60587.1
5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.997
SDM38622.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
 
0.967
SDM83445.1
O-acetylhomoserine (thiol)-lyase.
  
 
 0.961
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
  
 
 0.955
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.955
SDN00457.1
Homoserine dehydrogenase.
  
 
 0.950
SDM62644.1
Sarcosine oxidase.
  
 
 0.948
SDN30028.1
4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family.
  
 
 0.948
SDN66254.1
Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.
  
 
 0.948
SDN32397.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.931
Your Current Organism:
Allokutzneria albata
NCBI taxonomy Id: 211114
Other names: A. albata, ATCC 55061, DSM 44149, JCM 9917, Kibdelosporangium albatum, NBRC 101910, NRRL B-24461, strain R761-7
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