SDM37404.1 protein (Allokutzneria albata) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SDM37404.1

Alpha/beta hydrolase fold. (499 aa)

Predicted Functional Partners:

SDM52959.1

0.830

SDN03352.1

0.752

SDM29007.1

0.641

SDM57375.1

0.521

SDM61226.1

0.521

SDM37382.1

0.520

SDM25165.1

0.506

SDM25186.1

0.506

SDM31213.1

0.506

SDM31252.1

0.506

Your Current Organism:

Allokutzneria albata

NCBI taxonomy Id: 211114
Other names: A. albata, ATCC 55061, DSM 44149, JCM 9917, Kibdelosporangium albatum, NBRC 101910, NRRL B-24461, strain R761-7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDM25165.1	SDM25186.1	SAMN04489726_0597	SAMN04489726_0599	Erythronolide synthase docking.	Acyl transferase domain-containing protein.	0.992
SDM25165.1	SDM29007.1	SAMN04489726_0597	SAMN04489726_0814	Erythronolide synthase docking.	Phosphopantetheine attachment site.	0.995
SDM25165.1	SDM31213.1	SAMN04489726_0597	SAMN04489726_0931	Erythronolide synthase docking.	Polyketide synthase 12.	0.985
SDM25165.1	SDM31252.1	SAMN04489726_0597	SAMN04489726_0934	Erythronolide synthase docking.	Acyl transferase domain-containing protein.	0.985
SDM25165.1	SDM37404.1	SAMN04489726_0597	SAMN04489726_1304	Erythronolide synthase docking.	Alpha/beta hydrolase fold.	0.506
SDM25165.1	SDM52959.1	SAMN04489726_0597	SAMN04489726_2079	Erythronolide synthase docking.	Amino acid adenylation domain-containing protein.	0.999
SDM25165.1	SDM57375.1	SAMN04489726_0597	SAMN04489726_2320	Erythronolide synthase docking.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.992
SDM25165.1	SDM61226.1	SAMN04489726_0597	SAMN04489726_2501	Erythronolide synthase docking.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.992
SDM25165.1	SDN03352.1	SAMN04489726_0597	SAMN04489726_4562	Erythronolide synthase docking.	Acyl transferase domain-containing protein.	0.996
SDM25186.1	SDM25165.1	SAMN04489726_0599	SAMN04489726_0597	Acyl transferase domain-containing protein.	Erythronolide synthase docking.	0.992
SDM25186.1	SDM29007.1	SAMN04489726_0599	SAMN04489726_0814	Acyl transferase domain-containing protein.	Phosphopantetheine attachment site.	0.995
SDM25186.1	SDM31213.1	SAMN04489726_0599	SAMN04489726_0931	Acyl transferase domain-containing protein.	Polyketide synthase 12.	0.987
SDM25186.1	SDM31252.1	SAMN04489726_0599	SAMN04489726_0934	Acyl transferase domain-containing protein.	Acyl transferase domain-containing protein.	0.987
SDM25186.1	SDM37404.1	SAMN04489726_0599	SAMN04489726_1304	Acyl transferase domain-containing protein.	Alpha/beta hydrolase fold.	0.506
SDM25186.1	SDM52959.1	SAMN04489726_0599	SAMN04489726_2079	Acyl transferase domain-containing protein.	Amino acid adenylation domain-containing protein.	0.999
SDM25186.1	SDM57375.1	SAMN04489726_0599	SAMN04489726_2320	Acyl transferase domain-containing protein.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.991
SDM25186.1	SDM61226.1	SAMN04489726_0599	SAMN04489726_2501	Acyl transferase domain-containing protein.	Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.	0.991
SDM25186.1	SDN03352.1	SAMN04489726_0599	SAMN04489726_4562	Acyl transferase domain-containing protein.	Acyl transferase domain-containing protein.	0.996
SDM29007.1	SDM25165.1	SAMN04489726_0814	SAMN04489726_0597	Phosphopantetheine attachment site.	Erythronolide synthase docking.	0.995
SDM29007.1	SDM25186.1	SAMN04489726_0814	SAMN04489726_0599	Phosphopantetheine attachment site.	Acyl transferase domain-containing protein.	0.995

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Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.687

expected number of edges:

18

PPI enrichment p-value:

0.0101

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006865

Amino acid transport

5 of 49

1.86

2.28

9.20e-06

GO:0015803

Branched-chain amino acid transport

2 of 2

2.85

1.37

0.0033

GO:0003333

Amino acid transmembrane transport

2 of 8

2.24

0.91

0.0206

GO:0000160

Phosphorelay signal transduction system

4 of 219

1.11

0.61

0.0315

GO:0006810

Transport

6 of 718

0.77

0.46

0.0315

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003723

RNA binding

4 of 116

1.38

0.82

0.0148

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009274

Peptidoglycan-based cell wall

4 of 302

0.97

0.55

0.0314

GO:0005886

Plasma membrane

9 of 1854

0.53

0.37

0.0134

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9153

Mixed, incl. Leucine-binding protein domain, and ANTAR domain

10 of 13

2.73

10.83

1.00e-22

CL:9168

Branched-chain amino acid transport, and Leucine-binding protein domain

5 of 5

2.85

5.17

2.13e-10

CL:9155

ANTAR domain, and Leucine-binding protein domain

3 of 5

2.63

2.37

4.04e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

6 of 380

1.05

0.9

0.00080

map02024

Quorum sensing

5 of 302

1.07

0.83

0.0026

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005561

ANTAR domain

3 of 5

2.63

1.95

0.00026

IPR029016

GAF-like domain superfamily

4 of 34

1.92

1.75

0.00026

IPR003018

GAF domain

3 of 16

2.12

1.47

0.0015

IPR028081

Leucine-binding protein domain

2 of 3

2.67

1.1

0.0101

IPR012074

GAF-ANTAR transcription anti-termination regulator, putative

2 of 3

2.67

1.1

0.0101

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01012

ANTAR (AmiR and NasR transcription antitermination regulators) is an RNA-binding domain found in bacterial transcription antitermination regulatory proteins. The majority of the domain consists of a coiled-coil.

3 of 5

2.63

2.68

1.02e-05

SM00065

Domain present in phytochromes and cGMP-specific phosphodiesterases.

4 of 22

2.11

2.58

5.57e-06

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