node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM19964.1 | SDM38622.1 | SAMN04489726_0319 | SAMN04489726_1366 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.967 |
SDM19964.1 | SDM62644.1 | SAMN04489726_0319 | SAMN04489726_2579 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sarcosine oxidase. | 0.948 |
SDM19964.1 | SDM88819.1 | SAMN04489726_0319 | SAMN04489726_3851 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADPH/NADH) large chain. | 0.546 |
SDM19964.1 | SDN30028.1 | SAMN04489726_0319 | SAMN04489726_5945 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family. | 0.948 |
SDM19964.1 | SDN66254.1 | SAMN04489726_0319 | SAMN04489726_7642 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.948 |
SDM19964.1 | gcvP | SAMN04489726_0319 | SAMN04489726_2987 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.845 |
SDM38622.1 | SDM19964.1 | SAMN04489726_1366 | SAMN04489726_0319 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.967 |
SDM38622.1 | SDM62644.1 | SAMN04489726_1366 | SAMN04489726_2579 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sarcosine oxidase. | 0.948 |
SDM38622.1 | SDM88819.1 | SAMN04489726_1366 | SAMN04489726_3851 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADPH/NADH) large chain. | 0.546 |
SDM38622.1 | SDN30028.1 | SAMN04489726_1366 | SAMN04489726_5945 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family. | 0.948 |
SDM38622.1 | SDN66254.1 | SAMN04489726_1366 | SAMN04489726_7642 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.948 |
SDM38622.1 | gcvP | SAMN04489726_1366 | SAMN04489726_2987 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.845 |
SDM62644.1 | SDM19964.1 | SAMN04489726_2579 | SAMN04489726_0319 | Sarcosine oxidase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
SDM62644.1 | SDM38622.1 | SAMN04489726_2579 | SAMN04489726_1366 | Sarcosine oxidase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
SDM62644.1 | SDM88819.1 | SAMN04489726_2579 | SAMN04489726_3851 | Sarcosine oxidase. | Glutamate synthase (NADPH/NADH) large chain. | 0.961 |
SDM62644.1 | SDM91477.1 | SAMN04489726_2579 | SAMN04489726_3976 | Sarcosine oxidase. | Glycine cleavage system H protein. | 0.977 |
SDM62644.1 | SDN11632.1 | SAMN04489726_2579 | SAMN04489726_4997 | Sarcosine oxidase. | NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase. | 0.950 |
SDM62644.1 | SDN30028.1 | SAMN04489726_2579 | SAMN04489726_5945 | Sarcosine oxidase. | 4-methylaminobutanoate oxidase (formaldehyde-forming); Belongs to the GcvT family. | 0.996 |
SDM62644.1 | SDN45995.1 | SAMN04489726_2579 | SAMN04489726_6709 | Sarcosine oxidase. | 2-oxoglutarate decarboxylase. | 0.953 |
SDM62644.1 | SDN66254.1 | SAMN04489726_2579 | SAMN04489726_7642 | Sarcosine oxidase. | Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family. | 0.995 |