node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM31163.1 | SDM75368.1 | SAMN04489726_0928 | SAMN04489726_3220 | 2,4-dienoyl-CoA reductase (NADPH2). | Peptidase family M1. | 0.419 |
SDM50956.1 | SDM75368.1 | SAMN04489726_1986 | SAMN04489726_3220 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Peptidase family M1. | 0.480 |
SDM50956.1 | glyA | SAMN04489726_1986 | SAMN04489726_1954 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.648 |
SDM50956.1 | glyA-2 | SAMN04489726_1986 | SAMN04489726_4405 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.648 |
SDM75368.1 | SDM31163.1 | SAMN04489726_3220 | SAMN04489726_0928 | Peptidase family M1. | 2,4-dienoyl-CoA reductase (NADPH2). | 0.419 |
SDM75368.1 | SDM50956.1 | SAMN04489726_3220 | SAMN04489726_1986 | Peptidase family M1. | Non-ribosomal peptide synthetase terminal domain of unknown function. | 0.480 |
SDM75368.1 | SDM75391.1 | SAMN04489726_3220 | SAMN04489726_3221 | Peptidase family M1. | Serine/threonine protein phosphatase PrpC. | 0.418 |
SDM75368.1 | SDN02142.1 | SAMN04489726_3220 | SAMN04489726_4500 | Peptidase family M1. | Non-ribosomal peptide synthetase terminal domain of unknown function. | 0.469 |
SDM75368.1 | SDN09117.1 | SAMN04489726_3220 | SAMN04489726_4864 | Peptidase family M1. | Leucyl aminopeptidase; Belongs to the peptidase M17 family. | 0.514 |
SDM75368.1 | SDN46943.1 | SAMN04489726_3220 | SAMN04489726_6748 | Peptidase family M1. | Non-ribosomal peptide synthetase terminal domain of unknown function. | 0.502 |
SDM75368.1 | glyA | SAMN04489726_3220 | SAMN04489726_1954 | Peptidase family M1. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.502 |
SDM75368.1 | glyA-2 | SAMN04489726_3220 | SAMN04489726_4405 | Peptidase family M1. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.502 |
SDM75368.1 | pepA | SAMN04489726_3220 | SAMN04489726_7323 | Peptidase family M1. | Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. | 0.514 |
SDM75391.1 | SDM75368.1 | SAMN04489726_3221 | SAMN04489726_3220 | Serine/threonine protein phosphatase PrpC. | Peptidase family M1. | 0.418 |
SDN02142.1 | SDM75368.1 | SAMN04489726_4500 | SAMN04489726_3220 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Peptidase family M1. | 0.469 |
SDN02142.1 | glyA | SAMN04489726_4500 | SAMN04489726_1954 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.648 |
SDN02142.1 | glyA-2 | SAMN04489726_4500 | SAMN04489726_4405 | Non-ribosomal peptide synthetase terminal domain of unknown function. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.648 |
SDN09117.1 | SDM75368.1 | SAMN04489726_4864 | SAMN04489726_3220 | Leucyl aminopeptidase; Belongs to the peptidase M17 family. | Peptidase family M1. | 0.514 |
SDN09117.1 | glyA | SAMN04489726_4864 | SAMN04489726_1954 | Leucyl aminopeptidase; Belongs to the peptidase M17 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.789 |
SDN09117.1 | glyA-2 | SAMN04489726_4864 | SAMN04489726_4405 | Leucyl aminopeptidase; Belongs to the peptidase M17 family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.789 |