SDM87681.1 protein (Allokutzneria albata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

SDM87681.1

Carbohydrate ABC transporter substrate-binding protein, CUT1 family. (439 aa)

Predicted Functional Partners:

SDM87645.1

0.969

SDM87662.1

0.968

SDM87623.1

0.897

SDM87601.1

0.815

SDM31610.1

0.640

SDM15570.1

0.621

SDM90288.1

0.579

SDN08666.1

0.579

SDN35379.1

0.579

SDM87709.1

0.552

Your Current Organism:

Allokutzneria albata

NCBI taxonomy Id: 211114
Other names: A. albata, ATCC 55061, DSM 44149, JCM 9917, Kibdelosporangium albatum, NBRC 101910, NRRL B-24461, strain R761-7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDM15570.1	SDM87645.1	SAMN04489726_0064	SAMN04489726_3797	L-fucose isomerase.	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	0.404
SDM15570.1	SDM87662.1	SAMN04489726_0064	SAMN04489726_3798	L-fucose isomerase.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.409
SDM15570.1	SDM87681.1	SAMN04489726_0064	SAMN04489726_3799	L-fucose isomerase.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.621
SDM31610.1	SDM87681.1	SAMN04489726_0957	SAMN04489726_3799	three-Cys-motif partner protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.640
SDM87601.1	SDM87623.1	SAMN04489726_3795	SAMN04489726_3796	Hypothetical protein.	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	0.776
SDM87601.1	SDM87645.1	SAMN04489726_3795	SAMN04489726_3797	Hypothetical protein.	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	0.710
SDM87601.1	SDM87662.1	SAMN04489726_3795	SAMN04489726_3798	Hypothetical protein.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.719
SDM87601.1	SDM87681.1	SAMN04489726_3795	SAMN04489726_3799	Hypothetical protein.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.815
SDM87601.1	SDM87709.1	SAMN04489726_3795	SAMN04489726_3800	Hypothetical protein.	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	0.479
SDM87623.1	SDM87601.1	SAMN04489726_3796	SAMN04489726_3795	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Hypothetical protein.	0.776
SDM87623.1	SDM87645.1	SAMN04489726_3796	SAMN04489726_3797	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	0.998
SDM87623.1	SDM87662.1	SAMN04489726_3796	SAMN04489726_3798	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.982
SDM87623.1	SDM87681.1	SAMN04489726_3796	SAMN04489726_3799	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.897
SDM87623.1	SDM87709.1	SAMN04489726_3796	SAMN04489726_3800	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain.	0.485
SDM87623.1	SDN08666.1	SAMN04489726_3796	SAMN04489726_4836	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	0.743
SDM87645.1	SDM15570.1	SAMN04489726_3797	SAMN04489726_0064	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	L-fucose isomerase.	0.404
SDM87645.1	SDM87601.1	SAMN04489726_3797	SAMN04489726_3795	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	Hypothetical protein.	0.710
SDM87645.1	SDM87623.1	SAMN04489726_3797	SAMN04489726_3796	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	Carbohydrate ABC transporter ATP-binding protein, CUT1 family; Belongs to the ABC transporter superfamily.	0.998
SDM87645.1	SDM87662.1	SAMN04489726_3797	SAMN04489726_3798	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	Carbohydrate ABC transporter membrane protein 1, CUT1 family.	0.978
SDM87645.1	SDM87681.1	SAMN04489726_3797	SAMN04489726_3799	Carbohydrate ABC transporter membrane protein 2, CUT1 family.	Carbohydrate ABC transporter substrate-binding protein, CUT1 family.	0.969

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Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.809

expected number of edges:

10

PPI enrichment p-value:

0.000777

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019665

Anaerobic amino acid catabolic process

9 of 27

2.01

5.24

3.72e-14

GO:0019670

Anaerobic glutamate catabolic process

7 of 15

2.16

4.9

1.07e-11

GO:0019752

Carboxylic acid metabolic process

10 of 332

0.97

1.13

7.13e-08

GO:0019475

L-lysine catabolic process to acetate

2 of 12

1.71

0.71

0.0420

GO:1901564

Organonitrogen compound metabolic process

10 of 707

0.64

0.56

8.92e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008410

CoA-transferase activity

7 of 17

2.1

4.48

7.13e-11

GO:0016740

Transferase activity

8 of 483

0.71

0.52

0.0044

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:35757244

(2022) Regulatory Effect of Mung Bean Peptide on Prediabetic Mice Induced by High-Fat Diet.

3 of 5

2.27

2.38

2.40e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5576

Lysine degradation

11 of 20

2.23

8.17

3.71e-21

CL:5577

Coenzyme A transferase, and Beta-keto acid cleavage enzyme

7 of 12

2.25

5.45

1.32e-12

CL:5581

Coenzyme A transferase

5 of 6

2.41

4.22

4.19e-09

CL:5602

Intramolecular transferase activity, transferring amino groups, and GroES-like superfamily

2 of 5

2.09

1.0

0.0134

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ibu00310

Lysine degradation

10 of 27

2.06

6.41

6.80e-18

ibu00640

Propanoate metabolism

7 of 40

1.73

3.25

9.58e-10

ibu00650

Butanoate metabolism

7 of 47

1.66

3.0

1.78e-09

ibu02020

Two-component system

7 of 62

1.54

2.56

8.03e-09

ibu01120

Microbial metabolism in diverse environments

7 of 155

1.14

1.35

2.29e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

9 of 705

0.59

0.43

0.0067

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

7 of 388

0.74

0.51

0.0112

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004165

Coenzyme A transferase family I

7 of 11

2.29

5.13

1.33e-11

IPR037171

NagB/RpiA transferase-like

7 of 22

1.99

4.02

3.22e-10

IPR012792

3-oxoacid CoA-transferase, subunit A

4 of 4

2.49

3.02

1.81e-06

IPR012791

3-oxoacid CoA-transferase, subunit B

3 of 4

2.36

1.88

0.00029

IPR004164

Coenzyme A transferase active site

2 of 3

2.31

0.87

0.0248

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00882

Coenzyme A transferase

7 of 11

2.29

5.55

1.14e-12

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