SDN50343.1 protein (Allokutzneria albata) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SDN50343.1

Ca2+-binding protein, EF-hand superfamily. (179 aa)

Predicted Functional Partners:

gmk

0.939

SDM99218.1

0.873

SDM17658.1

0.840

SDN72486.1

0.840

SDM39667.1

0.806

SDN42545.1

0.806

SDM17130.1

0.785

SDM20627.1

0.785

SDM35248.1

0.785

SDM53621.1

0.785

Your Current Organism:

Allokutzneria albata

NCBI taxonomy Id: 211114
Other names: A. albata, ATCC 55061, DSM 44149, JCM 9917, Kibdelosporangium albatum, NBRC 101910, NRRL B-24461, strain R761-7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDM17130.1	SDM99218.1	SAMN04489726_0150	SAMN04489726_4360	Ankyrin repeat.	Protein of unknown function.	0.894
SDM17130.1	SDN50343.1	SAMN04489726_0150	SAMN04489726_6903	Ankyrin repeat.	Ca2+-binding protein, EF-hand superfamily.	0.785
SDM17130.1	gmk	SAMN04489726_0150	SAMN04489726_7879	Ankyrin repeat.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.766
SDM17658.1	SDM99218.1	SAMN04489726_0182	SAMN04489726_4360	FKBP-type peptidyl-prolyl cis-trans isomerase.	Protein of unknown function.	0.864
SDM17658.1	SDN50343.1	SAMN04489726_0182	SAMN04489726_6903	FKBP-type peptidyl-prolyl cis-trans isomerase.	Ca2+-binding protein, EF-hand superfamily.	0.840
SDM20627.1	SDM99218.1	SAMN04489726_0355	SAMN04489726_4360	DinB superfamily protein.	Protein of unknown function.	0.894
SDM20627.1	SDN50343.1	SAMN04489726_0355	SAMN04489726_6903	DinB superfamily protein.	Ca2+-binding protein, EF-hand superfamily.	0.785
SDM20627.1	gmk	SAMN04489726_0355	SAMN04489726_7879	DinB superfamily protein.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.766
SDM35248.1	SDM99218.1	SAMN04489726_1202	SAMN04489726_4360	Hypothetical protein.	Protein of unknown function.	0.894
SDM35248.1	SDN50343.1	SAMN04489726_1202	SAMN04489726_6903	Hypothetical protein.	Ca2+-binding protein, EF-hand superfamily.	0.785
SDM35248.1	gmk	SAMN04489726_1202	SAMN04489726_7879	Hypothetical protein.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.766
SDM39667.1	SDN42545.1	SAMN04489726_1417	SAMN04489726_6560	Aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.712
SDM39667.1	SDN50343.1	SAMN04489726_1417	SAMN04489726_6903	Aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Ca2+-binding protein, EF-hand superfamily.	0.806
SDM53621.1	SDM99218.1	SAMN04489726_2113	SAMN04489726_4360	Hypothetical protein.	Protein of unknown function.	0.894
SDM53621.1	SDN50343.1	SAMN04489726_2113	SAMN04489726_6903	Hypothetical protein.	Ca2+-binding protein, EF-hand superfamily.	0.785
SDM53621.1	gmk	SAMN04489726_2113	SAMN04489726_7879	Hypothetical protein.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.766
SDM99218.1	SDM17130.1	SAMN04489726_4360	SAMN04489726_0150	Protein of unknown function.	Ankyrin repeat.	0.894
SDM99218.1	SDM17658.1	SAMN04489726_4360	SAMN04489726_0182	Protein of unknown function.	FKBP-type peptidyl-prolyl cis-trans isomerase.	0.864
SDM99218.1	SDM20627.1	SAMN04489726_4360	SAMN04489726_0355	Protein of unknown function.	DinB superfamily protein.	0.894
SDM99218.1	SDM35248.1	SAMN04489726_4360	SAMN04489726_1202	Protein of unknown function.	Hypothetical protein.	0.894

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.915

expected number of edges:

13

PPI enrichment p-value:

0.00139

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030198

Extracellular matrix organization

3 of 3

2.58

1.93

0.00027

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008658

Penicillin binding

6 of 22

2.02

3.53

1.27e-08

GO:0005201

Extracellular matrix structural constituent

3 of 3

2.58

2.5

2.21e-05

GO:0008955

Peptidoglycan glycosyltransferase activity

2 of 5

2.19

1.08

0.0095

GO:0009002

Serine-type D-Ala-D-Ala carboxypeptidase activity

2 of 9

1.93

0.87

0.0220

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031012

Extracellular matrix

3 of 3

2.58

2.43

2.96e-05

GO:0005615

Extracellular space

3 of 3

2.58

2.43

2.96e-05

GO:0005887

Integral component of plasma membrane

4 of 78

1.29

1.11

0.0011

GO:0071944

Cell periphery

7 of 655

0.61

0.44

0.0067

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2028

Mixed, incl. Penicillin-binding protein, transpeptidase, and Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal

6 of 12

2.28

4.57

3.03e-10

CL:1996

Peptidoglycan biosynthesis, and Alanine racemase

7 of 29

1.97

4.01

2.39e-10

CL:2030

Penicillin-binding protein, transpeptidase, and Cell cycle, FtsW / RodA / SpoVE, conserved site

4 of 6

2.41

3.28

4.40e-07

CL:1986

Mixed, incl. Peptidoglycan biosynthesis, and Extracellular region

10 of 140

1.44

2.62

2.11e-11

CL:2169

Mixed, incl. Extracellular space, and Xylanase activity

3 of 20

1.76

1.34

0.0017

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 42

1.74

2.79

7.49e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005576

Extracellular region

4 of 98

1.2

0.69

0.0221

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00905

Penicillin binding protein transpeptidase domain

4 of 7

2.34

2.78

4.06e-06

PF03717

Penicillin-binding Protein dimerisation domain

3 of 3

2.58

2.25

6.54e-05

PF01391

Collagen triple helix repeat (20 copies)

2 of 3

2.41

1.08

0.0102

PF00912

Transglycosylase

2 of 4

2.28

1.05

0.0115

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001460

Penicillin-binding protein, transpeptidase

4 of 7

2.34

2.59

1.01e-05

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

3 of 3

2.58

2.14

0.00011

IPR005311

Penicillin-binding protein, dimerisation domain

3 of 3

2.58

2.14

0.00011

IPR012338

Beta-lactamase/transpeptidase-like

4 of 17

1.96

1.97

9.00e-05

IPR008160

Collagen triple helix repeat

2 of 2

2.58

1.12

0.0092

(more ...)

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