PCC6912_21750 protein (Chlorogloeopsis fritschii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PCC6912_21750

Unannotated protein. (421 aa)

Predicted Functional Partners:

PCC6912_22020

0.793

PCC6912_56060

0.786

PCC6912_41440

0.781

PCC6912_25820

0.778

GCA_000317285_03320

0.777

PCC6912_31040

0.774

PCC6912_29130

0.774

PCC6912_02960

0.774

PCC6912_16740

0.773

PCC6912_43950

0.772

Your Current Organism:

Chlorogloeopsis fritschii

NCBI taxonomy Id: 211165
Other names: C. fritschii PCC 6912, Chlorogloeopsis fritschii PCC 6912, Chlorogloeopsis fritschii str. PCC 6912, Chlorogloeopsis sp. ATCC 27193, Chlorogloeopsis sp. DSM 101459, Chlorogloeopsis sp. PCC 6912

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCA_000317285_03320	PCC6912_21750	GCA_000317285_03320	GCA_000317285_04715	Unannotated protein.	Unannotated protein.	0.777
GCA_000317285_03320	PCC6912_22020	GCA_000317285_03320	GCA_000317285_04743	Unannotated protein.	Unannotated protein.	0.992
GCA_000317285_03320	PCC6912_41440	GCA_000317285_03320	GCA_000317285_02632	Unannotated protein.	Unannotated protein.	0.992
GCA_000317285_03320	PCC6912_43950	GCA_000317285_03320	GCA_000317285_03454	Unannotated protein.	Unannotated protein.	0.999
GCA_000317285_03320	PCC6912_56060	GCA_000317285_03320	GCA_000317285_03321	Unannotated protein.	Unannotated protein.	0.999
PCC6912_02960	PCC6912_16740	GCA_000317285_05207	GCA_000317285_00933	Unannotated protein.	Unannotated protein.	0.739
PCC6912_02960	PCC6912_21750	GCA_000317285_05207	GCA_000317285_04715	Unannotated protein.	Unannotated protein.	0.774
PCC6912_02960	PCC6912_22020	GCA_000317285_05207	GCA_000317285_04743	Unannotated protein.	Unannotated protein.	0.434
PCC6912_02960	PCC6912_25820	GCA_000317285_05207	GCA_000317285_04096	Unannotated protein.	Unannotated protein.	0.770
PCC6912_02960	PCC6912_29130	GCA_000317285_05207	GCA_000317285_02482	Unannotated protein.	Unannotated protein.	0.773
PCC6912_02960	PCC6912_31040	GCA_000317285_05207	GCA_000317285_01342	Unannotated protein.	Unannotated protein.	0.773
PCC6912_16740	PCC6912_02960	GCA_000317285_00933	GCA_000317285_05207	Unannotated protein.	Unannotated protein.	0.739
PCC6912_16740	PCC6912_21750	GCA_000317285_00933	GCA_000317285_04715	Unannotated protein.	Unannotated protein.	0.773
PCC6912_16740	PCC6912_29130	GCA_000317285_00933	GCA_000317285_02482	Unannotated protein.	Unannotated protein.	0.772
PCC6912_16740	PCC6912_31040	GCA_000317285_00933	GCA_000317285_01342	Unannotated protein.	Unannotated protein.	0.751
PCC6912_21750	GCA_000317285_03320	GCA_000317285_04715	GCA_000317285_03320	Unannotated protein.	Unannotated protein.	0.777
PCC6912_21750	PCC6912_02960	GCA_000317285_04715	GCA_000317285_05207	Unannotated protein.	Unannotated protein.	0.774
PCC6912_21750	PCC6912_16740	GCA_000317285_04715	GCA_000317285_00933	Unannotated protein.	Unannotated protein.	0.773
PCC6912_21750	PCC6912_22020	GCA_000317285_04715	GCA_000317285_04743	Unannotated protein.	Unannotated protein.	0.793
PCC6912_21750	PCC6912_25820	GCA_000317285_04715	GCA_000317285_04096	Unannotated protein.	Unannotated protein.	0.778

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.875

expected number of edges:

11

PPI enrichment p-value:

4.94e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009252

Peptidoglycan biosynthetic process

8 of 38

1.96

4.42

8.65e-12

GO:0071555

Cell wall organization

4 of 26

1.83

2.07

2.98e-05

GO:0008360

Regulation of cell shape

4 of 26

1.83

2.07

2.98e-05

GO:0051301

Cell division

3 of 44

1.47

0.99

0.0063

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008955

Peptidoglycan glycosyltransferase activity

5 of 7

2.49

4.05

1.40e-08

GO:0008658

Penicillin binding

4 of 6

2.46

3.21

7.03e-07

GO:0009002

Serine-type D-Ala-D-Ala carboxypeptidase activity

3 of 5

2.42

2.34

3.71e-05

GO:0016757

Glycosyltransferase activity

6 of 61

1.63

2.33

7.03e-07

GO:0004180

Carboxypeptidase activity

4 of 19

1.96

2.32

1.32e-05

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1359

Mixed, incl. Peptidoglycan biosynthesis, and Cell division

11 of 46

2.02

6.54

2.68e-19

CL:1363

Mixed, incl. Peptidoglycan biosynthesis, and Cell division site

9 of 33

2.07

5.85

1.83e-15

CL:1416

Peptidoglycan glycosyltransferase activity, and Peptidoglycan muralytic activity

4 of 5

2.54

3.48

2.33e-07

CL:1365

Mixed, incl. Cell shape, and Cell division site

5 of 23

1.98

3.01

2.35e-07

CL:1398

Mixed, incl. Cell cycle protein, and Cell morphogenesis

2 of 5

2.24

1.07

0.0102

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00550

Peptidoglycan biosynthesis

6 of 33

1.9

3.33

1.15e-08

map01501

beta-Lactam resistance

4 of 121

1.16

0.79

0.0083

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0032153

Cell division site

3 of 9

2.16

1.68

0.00059

GOCC:0005618

Cell wall

3 of 21

1.79

1.26

0.0027

GOCC:0071944

Cell periphery

7 of 713

0.63

0.39

0.0319

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0961

Cell wall biogenesis/degradation

3 of 16

1.91

1.38

0.0018

KW-0133

Cell shape

3 of 16

1.91

1.38

0.0018

KW-0997

Cell inner membrane

3 of 42

1.49

0.94

0.0087

KW-0573

Peptidoglycan synthesis

2 of 15

1.76

0.87

0.0198

KW-0328

Glycosyltransferase

2 of 22

1.6

0.73

0.0348

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00905

Penicillin binding protein transpeptidase domain

4 of 6

2.46

2.98

2.11e-06

PF03717

Penicillin-binding Protein dimerisation domain

2 of 2

2.64

1.11

0.0097

PF01098

Cell cycle protein

2 of 2

2.64

1.11

0.0097

PF00912

Transglycosylase

2 of 4

2.34

1.04

0.0120

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001460

Penicillin-binding protein, transpeptidase

4 of 6

2.46

2.92

2.73e-06

IPR012338

Beta-lactamase/transpeptidase-like

5 of 18

2.08

2.84

1.26e-06

IPR036138

Penicillin-binding protein, dimerisation domain superfamily

2 of 2

2.64

0.98

0.0167

IPR005311

Penicillin-binding protein, dimerisation domain

2 of 2

2.64

0.98

0.0167

IPR001182

Probable peptidoglycan glycosyltransferase FtsW/RodA

2 of 2

2.64

0.98

0.0167

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (28%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About