STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaAChromosomal replication initiation protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
dnaB
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.944
AIA29775.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.828
secDF
Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.719
AIA29186.1
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.679
topA
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.665
dnaI
Putative primosomal protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 0.635
hup
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.628
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 0.622
dnaX
DNA polymerase III subunits gamma and tau; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.616
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.