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dnaN protein (Mycoplasma californicum) - STRING interaction network
"dnaN" - DNA polymerase III subunit beta in Mycoplasma californicum
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
dnaNDNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method- Protein Homology (368 aa)    
Predicted Functional Partners:
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method- Protein Homology (316 aa)
 
  0.996
dnaE
DNA-directed DNA polymerase; Catalyzes DNA-template-directed extension of the 3’-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria; Derived by automated computational analysis using gene prediction method- Protein Homology (969 aa)
       
  0.981
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (619 aa)
   
  0.976
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (472 aa)
   
 
  0.973
MCFN_03340
5’-3’ exonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (290 aa)
   
  0.973
polC
DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (1447 aa)
     
  0.963
dnaH
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology (305 aa)
 
  0.925
pyk
Pyruvate kinase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the pyruvate kinase family (476 aa)
   
    0.924
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (894 aa)
   
 
  0.902
dinB
DNA polymerase IV; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the DNA polymerase type-Y family (412 aa)
     
 
  0.874
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, Mycoplasma californicum, NCTC 10189, strain ST-6
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