STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yidCPreprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)    
Predicted Functional Partners:
secDF
Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.998
secY
Preprotein translocase subunit SecY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
rnpA
Ribonuclease P protein component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.974
ffh
With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.957
secG
Preprotein translocase subunit SecG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.952
secA
Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have [...]
  
 
 0.946
ftsY
Cell division protein FtsY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.942
secE
Preprotein translocase subunit SecE; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 
 0.866
rplD
50S ribosomal protein L4; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.862
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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