ackA-1 protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ackA-1

Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)

Predicted Functional Partners:

pta-2

0.996

pta-1

0.988

AIA29720.1

0.918

ackA-2

0.906

AIA29371.1

0.703

metS

0.461

AIA29781.1

0.413

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIA29371.1	ackA-1	MCFN_01075	MCFN_00140	Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
AIA29371.1	ackA-2	MCFN_01075	MCFN_01610	Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.760
AIA29371.1	pta-2	MCFN_01075	MCFN_01615	Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.932
AIA29720.1	AIA29781.1	MCFN_03025	MCFN_03370	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.446
AIA29720.1	ackA-1	MCFN_03025	MCFN_00140	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
AIA29720.1	ackA-2	MCFN_03025	MCFN_01610	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
AIA29720.1	pta-1	MCFN_03025	MCFN_00145	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.842
AIA29720.1	pta-2	MCFN_03025	MCFN_01615	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
AIA29781.1	AIA29720.1	MCFN_03370	MCFN_03025	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.446
AIA29781.1	ackA-1	MCFN_03370	MCFN_00140	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
AIA29781.1	ackA-2	MCFN_03370	MCFN_01610	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
AIA29781.1	metS	MCFN_03370	MCFN_00455	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
ackA-1	AIA29371.1	MCFN_00140	MCFN_01075	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.703
ackA-1	AIA29720.1	MCFN_00140	MCFN_03025	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
ackA-1	AIA29781.1	MCFN_00140	MCFN_03370	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
ackA-1	ackA-2	MCFN_00140	MCFN_01610	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
ackA-1	metS	MCFN_00140	MCFN_00455	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.461
ackA-1	pta-1	MCFN_00140	MCFN_00145	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
ackA-1	pta-2	MCFN_00140	MCFN_01615	Acetate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
ackA-2	AIA29371.1	MCFN_01610	MCFN_01075	Acetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.760