tig protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tig

Peptidylprolyl isomerase (trigger factor); Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)

Predicted Functional Partners:

rpsD

0.984

rpsB

0.983

rpsG

0.982

rplD

0.981

rplC

0.981

rplM

0.980

rpsL

0.978

rplB

0.978

rplU

0.977

rpsF

0.976

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rplB	rplC	MCFN_02405	MCFN_02420	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
rplB	rplD	MCFN_02405	MCFN_02415	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L4; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
rplB	rplM	MCFN_02405	MCFN_02890	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
rplB	rplU	MCFN_02405	MCFN_00835	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L21; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
rplB	rpsB	MCFN_02405	MCFN_01550	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
rplB	rpsD	MCFN_02405	MCFN_01280	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S4; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
rplB	rpsF	MCFN_02405	MCFN_02040	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S6.	0.988
rplB	rpsG	MCFN_02405	MCFN_00495	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.989
rplB	rpsL	MCFN_02405	MCFN_00490	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.989
rplB	tig	MCFN_02405	MCFN_00210	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Peptidylprolyl isomerase (trigger factor); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.978
rplC	rplB	MCFN_02420	MCFN_02405	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.999
rplC	rplD	MCFN_02420	MCFN_02415	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L4; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
rplC	rplM	MCFN_02420	MCFN_02890	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
rplC	rplU	MCFN_02420	MCFN_00835	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L21; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
rplC	rpsB	MCFN_02420	MCFN_01550	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
rplC	rpsD	MCFN_02420	MCFN_01280	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S4; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.989
rplC	rpsF	MCFN_02420	MCFN_02040	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S6.	0.988
rplC	rpsG	MCFN_02420	MCFN_00495	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.989
rplC	rpsL	MCFN_02420	MCFN_00490	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.989
rplC	tig	MCFN_02420	MCFN_00210	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidylprolyl isomerase (trigger factor); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.981