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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIA29317.1Integrase-recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)    
Predicted Functional Partners:
hsdS-2
Type I restriction modification system specificity subunit HsdS; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.888
topA
DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.741
AIA29775.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.730
hsdS-1
Type I restriction modification system specificity subunit HsdS; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.727
ruvB
Holliday junction DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.608
ruvA
Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.585
hsdM
Type I restriction-modification system M subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.556
uvrB
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.550
apt
Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.544
uvrA
Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.527
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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