secDF protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

secDF

Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (880 aa)

Predicted Functional Partners:

yidC

0.998

secY

0.997

secG

0.974

secA

0.972

ftsY

0.961

ffh

0.960

lspA

0.913

secE

0.900

AIA29205.1

0.856

pheT

0.856

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIA29205.1	ffh	MCFN_00120	MCFN_02170	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.566
AIA29205.1	ftsY	MCFN_00120	MCFN_02985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Cell division protein FtsY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.572
AIA29205.1	pheT	MCFN_00120	MCFN_02525	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.648
AIA29205.1	secA	MCFN_00120	MCFN_02930	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have [...]	0.420
AIA29205.1	secDF	MCFN_00120	MCFN_01325	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.856
AIA29205.1	secG	MCFN_00120	MCFN_00925	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Preprotein translocase subunit SecG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.527
AIA29205.1	secY	MCFN_00120	MCFN_01460	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Preprotein translocase subunit SecY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.580
AIA29205.1	yidC	MCFN_00120	MCFN_00045	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.400
ffh	AIA29205.1	MCFN_02170	MCFN_00120	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.566
ffh	ftsY	MCFN_02170	MCFN_02985	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Cell division protein FtsY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
ffh	lspA	MCFN_02170	MCFN_01200	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lipoprotein signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.408
ffh	pheT	MCFN_02170	MCFN_02525	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.577
ffh	secA	MCFN_02170	MCFN_02930	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have [...]	0.937
ffh	secDF	MCFN_02170	MCFN_01325	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.960
ffh	secE	MCFN_02170	MCFN_00075	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Preprotein translocase subunit SecE; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
ffh	secG	MCFN_02170	MCFN_00925	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Preprotein translocase subunit SecG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
ffh	secY	MCFN_02170	MCFN_01460	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Preprotein translocase subunit SecY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
ffh	yidC	MCFN_02170	MCFN_00045	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.957
ftsY	AIA29205.1	MCFN_02985	MCFN_00120	Cell division protein FtsY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.572
ftsY	ffh	MCFN_02985	MCFN_02170	Cell division protein FtsY; Derived by automated computational analysis using gene prediction method: Protein Homology.	With 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995