close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaGDNA primase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)    
Predicted Functional Partners:
dnaB
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
rpoD
RNA polymerase sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.983
AIA29775.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.920
glyS
glycyl-tRNA synthetase; Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.846
engA
GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.842
AIA29424.1
NIF3 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.822
recD
RecD/TraA family helicase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.814
dnaI
Putative primosomal protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.801
AIA29425.1
dUTPase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.761
dnaE
DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.757
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.