Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
secYPreprotein translocase subunit SecY; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)    
Predicted Functional Partners:
secDF
Bifunctional preprotein translocase subunit SecD/SecF; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.997
yidC
Preprotein translocase subunit YidC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
secA
Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have [...]
 
 0.993
adk
Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.992
rpsE
30S ribosomal protein S5; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.990
secG
Preprotein translocase subunit SecG; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.989
rplO
50S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.989
rplR
50S ribosomal protein L18; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
rplV
50S ribosomal protein L22; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.989
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
 
 
 0.988
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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