Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lonATP-dependent protease La; Derived by automated computational analysis using gene prediction method: Protein Homology. (941 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.897
ldh
L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.849
rpsB
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.831
ssb
Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.793
ileS
isoleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.792
grpE
Heat shock chaperone GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.792
rpsJ
30S ribosomal protein S10; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.773
rplL
50S ribosomal protein L7/L12; Present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.767
glyA
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.767
rpmF
50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.762
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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