holA protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

holA

DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)

Predicted Functional Partners:

dnaN

0.999

dnaX

0.999

dnaE

0.999

dnaH

0.997

polC

0.928

AIA29775.1

0.856

dnaB

0.716

AIA29711.1

0.656

dinB

0.645

topA

0.628

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIA29711.1	holA	MCFN_02980	MCFN_01575	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.656
AIA29775.1	dinB	MCFN_03340	MCFN_02875	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.962
AIA29775.1	dnaB	MCFN_03340	MCFN_00900	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.888
AIA29775.1	dnaE	MCFN_03340	MCFN_03345	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
AIA29775.1	dnaH	MCFN_03340	MCFN_02965	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.607
AIA29775.1	dnaN	MCFN_03340	MCFN_00010	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AIA29775.1	dnaX	MCFN_03340	MCFN_02945	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunits gamma and tau; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.607
AIA29775.1	holA	MCFN_03340	MCFN_01575	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.856
AIA29775.1	polC	MCFN_03340	MCFN_03010	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.866
AIA29775.1	topA	MCFN_03340	MCFN_02030	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.969
dinB	AIA29775.1	MCFN_02875	MCFN_03340	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.962
dinB	dnaE	MCFN_02875	MCFN_03345	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.825
dinB	dnaH	MCFN_02875	MCFN_02965	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.514
dinB	dnaN	MCFN_02875	MCFN_00010	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
dinB	dnaX	MCFN_02875	MCFN_02945	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunits gamma and tau; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.514
dinB	holA	MCFN_02875	MCFN_01575	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.645
dinB	topA	MCFN_02875	MCFN_02030	DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA topoisomerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.828
dnaB	AIA29775.1	MCFN_00900	MCFN_03340	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.888
dnaB	dnaE	MCFN_00900	MCFN_03345	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.764
dnaB	dnaH	MCFN_00900	MCFN_02965	DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.822