STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.991
ldh
L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.979
pgiB-2
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.956
fba
Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.938
tkt
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.934
pgiB-1
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.929
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.928
pdhB
Pyruvate dehydrogenase E1 component subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.926
rpsB
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.917
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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