STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)    
Predicted Functional Partners:
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 0.994
rplJ
50S ribosomal protein L10; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.992
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.992
rplF
50S ribosomal protein L6; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.992
rplE
50S ribosomal protein L5; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.992
rplX
50S ribosomal protein L24; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.992
rplR
50S ribosomal protein L18; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.991
rplN
50S ribosomal protein L14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.991
rplW
50S ribosomal protein L23; Binds third domain of 23S rRNA and protein L29; part of exit tunnel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.991
rplV
50S ribosomal protein L22; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.990
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.