STRINGSTRING
pcrA protein (Mycoplasma californicum) - STRING interaction network
"pcrA" - DNA helicase in Mycoplasma californicum
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcrADNA helicase; Derived by automated computational analysis using gene prediction method- Protein Homology (732 aa)    
Predicted Functional Partners:
asnS
Asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method- Protein Homology (453 aa)
              0.918
MCFN_01875
Glycosyl transferase; Derived by automated computational analysis using gene prediction method- Protein Homology (337 aa)
              0.918
uvrA
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (940 aa)
   
 
  0.878
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (662 aa)
   
 
  0.872
MCFN_01870
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- GeneMarkS+ (225 aa)
              0.861
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (660 aa)
   
 
  0.852
MCFN_01860
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- GeneMarkS+ (562 aa)
              0.845
MCFN_03340
5’-3’ exonuclease; Derived by automated computational analysis using gene prediction method- Protein Homology (290 aa)
 
 
  0.843
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5’ and 3’ sides of the lesion. The N-terminal half is responsible for the 3’ incision and the C-terminal half is responsible for the 5’ incision (572 aa)
 
     
  0.827
gtaB
UTP-glucose-1-phosphate uridyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (294 aa)
            0.802
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, Mycoplasma californicum, NCTC 10189, strain ST-6
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