Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rplC50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)    
Predicted Functional Partners:
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
  
 0.999
rplV
50S ribosomal protein L22; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 0.999
rplW
50S ribosomal protein L23; Binds third domain of 23S rRNA and protein L29; part of exit tunnel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
rplD
50S ribosomal protein L4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
rplO
50S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
rplR
50S ribosomal protein L18; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
rplF
50S ribosomal protein L6; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
rplE
50S ribosomal protein L5; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.998
rplN
50S ribosomal protein L14; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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