Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrABPeptide methionine sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)    
Predicted Functional Partners:
AIA29775.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.798
rpmJ
50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.785
grpE
Heat shock chaperone GrpE; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.782
rpsP
30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.755
rplL
50S ribosomal protein L7/L12; Present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.754
rpmB
50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.754
metK
S-adenosylmethionine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.680
clpB
ATP-dependent chaperone protein ClpB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.635
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.634
dnaK
Molecular chaperone DnaK; Heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.630
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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