rnc protein (Mycoplasma californicum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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[Homology]

Score

rnc

Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)

Predicted Functional Partners:

rplQ

0.897

rplS

0.896

rpmF

0.892

rplT

0.890

rplO

0.890

rplC

0.889

rplL

0.878

rplB

0.874

rplP

0.872

rpsI

0.870

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rnc	rplB	MCFN_02695	MCFN_02405	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.874
rnc	rplC	MCFN_02695	MCFN_02420	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.889
rnc	rplL	MCFN_02695	MCFN_00470	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L7/L12; Present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.878
rnc	rplO	MCFN_02695	MCFN_02330	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.890
rnc	rplP	MCFN_02695	MCFN_02385	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.872
rnc	rplQ	MCFN_02695	MCFN_01700	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
rnc	rplS	MCFN_02695	MCFN_00275	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L19; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.896
rnc	rplT	MCFN_02695	MCFN_01720	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.890
rnc	rpmF	MCFN_02695	MCFN_01220	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.892
rnc	rpsI	MCFN_02695	MCFN_02895	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.	0.870
rplB	rnc	MCFN_02405	MCFN_02695	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.874
rplB	rplC	MCFN_02405	MCFN_02420	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L3; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
rplB	rplL	MCFN_02405	MCFN_00470	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L7/L12; Present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
rplB	rplO	MCFN_02405	MCFN_02330	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
rplB	rplP	MCFN_02405	MCFN_02385	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.	0.999
rplB	rplQ	MCFN_02405	MCFN_01700	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
rplB	rplS	MCFN_02405	MCFN_00275	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L19; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
rplB	rplT	MCFN_02405	MCFN_01720	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.991
rplB	rpmF	MCFN_02405	MCFN_01220	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
rplB	rpsI	MCFN_02405	MCFN_02895	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.	0.989