Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lepAGTP-binding protein LepA; Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)    
Predicted Functional Partners:
rpsO
30S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.902
rplM
50S ribosomal protein L13; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.902
rplA
50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.900
rpsD
30S ribosomal protein S4; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.898
rpsB
30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.898
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 0.897
rpsF
30S ribosomal protein S6.
  
 
 0.895
rpmF
50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.894
rpsI
30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.894
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.892
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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