STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIA29702.1HAD superfamily hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)    
Predicted Functional Partners:
pgm
Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.782
AIA29485.1
COF family HAD hydrolase protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.748
AIA29376.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.670
AIA29756.1
COF family HAD hydrolase protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.649
AIA29246.1
COF family HAD hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.557
dnaX
DNA polymerase III subunits gamma and tau; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.526
secA
Preprotein translocase subunit SecA; Functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have [...]
       0.493
recR
Recombination protein RecR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.474
dnaH
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.451
AIA29705.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.430
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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