Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
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[Homology]
Score
tmkThymidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)    
Predicted Functional Partners:
rsmI
Ribosomal RNA small subunit methyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.883
dnaX
DNA polymerase III subunits gamma and tau; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.873
dnaH
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.843
AIA29705.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.836
recR
Recombination protein RecR; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.808
AIA29265.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.780
serS
seryl-tRNA synthetase; Catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.651
AIA29775.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.566
adk
Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.550
AIA29710.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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