engA protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

engA

GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)

Predicted Functional Partners:

cmk

0.992

dnaG

0.914

rplA

0.885

AIA29217.1

0.872

rplN

0.865

rplB

0.865

rplT

0.860

rplS

0.858

rpmA

0.857

rplQ

0.857

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIA29217.1	engA	MCFN_00190	MCFN_03075	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.872
AIA29217.1	rplA	MCFN_00190	MCFN_03160	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.825
AIA29217.1	rplB	MCFN_00190	MCFN_02405	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.822
AIA29217.1	rplN	MCFN_00190	MCFN_02370	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L14; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
AIA29217.1	rplQ	MCFN_00190	MCFN_01700	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.814
AIA29217.1	rplS	MCFN_00190	MCFN_00275	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L19; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
AIA29217.1	rplT	MCFN_00190	MCFN_01720	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.799
AIA29217.1	rpmA	MCFN_00190	MCFN_00840	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.786
cmk	engA	MCFN_03080	MCFN_03075	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
dnaG	engA	MCFN_01390	MCFN_03075	DNA primase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
engA	AIA29217.1	MCFN_03075	MCFN_00190	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.872
engA	cmk	MCFN_03075	MCFN_03080	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
engA	dnaG	MCFN_03075	MCFN_01390	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA primase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.914
engA	rplA	MCFN_03075	MCFN_03160	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.885
engA	rplB	MCFN_03075	MCFN_02405	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.865
engA	rplN	MCFN_03075	MCFN_02370	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L14; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.865
engA	rplQ	MCFN_03075	MCFN_01700	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.857
engA	rplS	MCFN_03075	MCFN_00275	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L19; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
engA	rplT	MCFN_03075	MCFN_01720	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.860
engA	rpmA	MCFN_03075	MCFN_00840	GTP-binding protein EngA (Der); Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.857