Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdhBPyruvate dehydrogenase E1 component subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
pdhC
Dihydrolipoamide acetyltransferase; Unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
pdhD
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
AIA29396.1
Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
ldh
L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.985
prs
Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.971
AIA29212.1
Lipoyl domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.970
pyk
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.926
AIA29345.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.913
tkt
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.866
Your Current Organism:
Mycoplasma californicum
NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6
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