apt protein (Mycoplasma californicum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

apt

Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)

Predicted Functional Partners:

adk

0.945

deoD

0.921

infB

0.833

nusA

0.807

AIA29769.1

0.806

rimP

0.788

gmk

0.572

metS

0.558

AIA29317.1

0.533

hpt

0.527

Your Current Organism:

Mycoplasma californicum

NCBI taxonomy Id: 2113
Other names: ATCC 33461, DSM 21477, M. californicum, NCTC 10189, strain ST-6

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIA29317.1	apt	MCFN_00790	MCFN_03315	Integrase-recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
AIA29769.1	apt	MCFN_03305	MCFN_03315	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.806
AIA29769.1	infB	MCFN_03305	MCFN_03310	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Translation initiation factor IF-2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.963
AIA29769.1	nusA	MCFN_03305	MCFN_03300	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor NusA; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.976
AIA29769.1	rimP	MCFN_03305	MCFN_03295	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribosome maturation factor RimP; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.812
adk	apt	MCFN_01455	MCFN_03315	Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
adk	gmk	MCFN_01455	MCFN_00930	Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.642
adk	hpt	MCFN_01455	MCFN_02770	Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
adk	metS	MCFN_01455	MCFN_00455	Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.544
apt	AIA29317.1	MCFN_03315	MCFN_00790	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Integrase-recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
apt	AIA29769.1	MCFN_03315	MCFN_03305	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.806
apt	adk	MCFN_03315	MCFN_01455	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.945
apt	deoD	MCFN_03315	MCFN_02590	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
apt	gmk	MCFN_03315	MCFN_00930	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.572
apt	hpt	MCFN_03315	MCFN_02770	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.527
apt	infB	MCFN_03315	MCFN_03310	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Translation initiation factor IF-2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.833
apt	metS	MCFN_03315	MCFN_00455	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methionyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
apt	nusA	MCFN_03315	MCFN_03300	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor NusA; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.807
apt	rimP	MCFN_03315	MCFN_03295	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribosome maturation factor RimP; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.788
deoD	apt	MCFN_02590	MCFN_03315	Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921